Title
Efficiency and safety of microporous polysaccharide hemispheres from potato starch in brain surgery
Authors
DANA MIHAELA TURLIUC ANDREI IONUT CUCU ALEXANDRU CĂRĂULEANU and CLAUDIA FLORIDA COSTEA

Received Dedicated to Acad. Bogdan C. Simionescu on the occasion of his 70^th anniversary
Published Volume 52 Issue 7-8 July-August
Keywords microporous polysaccharide hemispheres, potato starch, hemostasis, neurosurgery, brain surgery

Abstract
Efficient hemostasis is important in neurosurgery and in other surgical areas, in which bleeding is a challenge. Thus, topical hemostatic agents have become a highly important armamentarium. After the 2000s, surgery has come to use microporous polysaccharide hemispheres, natural macromolecular biopolymers obtained from potato starch, and over time, these hemostatic agents proved their efficiency and safety in performing topical hemostasis, both in clinical studies and in experimental ones. This article undertakes to highlight the advantages, the adverse reactions and the applicability of microporous polysaccharide hemispheres in the neurosurgical field and present new directions in chemical recombination of microporous polysaccharide hemispheres.