Title
Cellulose derivatives-based films with honey bee propolis extract: a novel approach to antibacterial and antioxidant materials
Authors
INDIRA RADHAKRISHNAN and VELLA DURAI SUBBAIAH CHELLADURAI

Received December 1, 2024
Published Volume 59 Issue 5-6 May-June
Keywords propolis extract, cellulose derivatives, polyvinylpyrrolidone, antibacterial activity, cytotoxicity test

Abstract
The research study aims to examine the incorporation of propolis extract and its effects on the biological properties of the thin films. These films are composed of non-ionic cellulose derivatives, specifically hydroxypropyl cellulose (HPC) and hydroxyethyl cellulose (HEC), combined with polyvinylpyrrolidone (PVP). The magnetic stirring method was used to prepare propolis extract (PE) from raw honey bee using an ethanol solution. The surface morphologies were analyzed by scanning electron microscopy. Antibacterial activity was examined against Staphylococcus aureus and it was observed that antibacterial activity significantly improved after the addition of the propolis extract. The 2,2-diphenyl-1 picrylhydrazyl (DPPH) radical assay was employed to evaluate antioxidant properties. The significant antibacterial and antioxidant properties of the material recommend it for potential biomedical applications.